Ryo Kumakami

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We previously found that Merkel cells (MCs) of the rat and monkey show a strong immunoreaction of the α-subunit of Gq protein. The Gαq-subunit isoform activates isozymes of phospholipase C-β (PLC-β), which produces inositol-(1,4,5)-triphosphate (IP3) which mobilizes intracellular Ca++ from calcium stores via IP3 receptors. Glutamate and adenosine(More)
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