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Mechanical ventilation support for acute respiratory distress syndrome (ARDS) patients involves the use of low tidal volumes and positive end-expiratory pressure. Nevertheless, the optimal ventilator strategy for ARDS patients undergoing extracorporeal membrane oxygenation (ECMO) therapy remains unknown. A retrospective analysis of a consecutive series of(More)
CONTEXT There is a controversy regarding the definition of vitamin D insufficiency as it relates to bone health. OBJECTIVE The objective of the study was to examine the evidence for a threshold value of serum 25-hydroxyvitamin D (25OHD) that defines vitamin D insufficiency as it relates to bone health. DESIGN AND PARTICIPANTS This was a cross-sectional(More)
OBJECTIVE To determine whether aerobic fitness is more salient than weight status in predicting performance on standardized math and reading tests in fourth- to eighth-grade students. STUDY DESIGN A cross-sectional study of data abstracted from 11,743 students in 47 public schools. Aerobic fitness was defined by entering the healthy fitness zone of(More)
BACKGROUND There is conflicting data regarding the mortality benefit of statins in patients with heart failure. The objectives of our study were to determine whether statin therapy is associated with decreased all-cause mortality and to assess the effect of incremental duration of therapy. METHODS We studied 10,510 consecutive patients from the Veterans(More)
OBJECTIVE We sought to determine whether the utilization of a respiratory therapist (RT) driven mechanical ventilation weaning protocol is associated with improvement in clinical outcomes in subjects with simple versus difficult weaning. METHODS This was a retrospective analysis of prospectively collected data obtained during a quality improvement(More)
OBJECTIVE Aggregated N-of-1 randomized controlled trials (RCTs) combined with multilevel modeling represent a methodological advancement that may help bridge science and practice in pediatric psychology. The purpose of this article is to offer a primer for pediatric psychologists interested in conducting aggregated N-of-1 RCTs. METHODS An overview of(More)
OBJECTIVE To develop a searchable database of educational technologies used at schools and colleges of pharmacy. METHODS A cross-sectional survey design was used to determine what educational technologies were being used and to identify an individual at each institution who could serve as an information resource for peer-to-peer questions. RESULTS(More)
OBJECTIVE To examine faculty members' and students' expectations and perceptions of e-mail communication in a dual pathway pharmacy program. METHODS Three parallel survey instruments were administered to campus students, distance students, and faculty members, respectively. Focus groups with students and faculty were conducted. RESULTS Faculty members(More)
Physical activity shows promise for protection against cognitive decline in older adults with and without Alzheimer's disease (AD). To better understand barriers to adoption of physical activity in this population, a clear understanding of daily and weekly activity patterns is needed. Most accelerometry studies report average physical activity over an(More)