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OBJECTIVE To assess feasibility and effects of training in goal-oriented attentional self-regulation for patients with brain injury and chronic executive dysfunction. PARTICIPANTS Sixteen individuals with chronic brain injury and mild to moderate executive dysfunction. DESIGN Participants were divided into 2 groups: one group completed goal-oriented(More)
Factors that regulate the formation, spatial patterning, and maturation of CNS synapses are poorly understood. We used organotypic hippocampal slice cultures derived from developing (P5-P7) rat to test whether synaptic activity regulates the development and organization of postsynaptic structures at mossy fiber (MF) giant synapses. Antibodies to a prominent(More)
The effects of tranylcypromine (TCP) HCl (4 mg/kg and 20 mg/kg i.p.) and phenelzine (PLZ) sulfate (10 mg/kg and 50 mg/kg) on levels of dopamine (DA), noradrenaline (NA), 5-hydroxytryptamine (5-HT), 3-methoxytyramine (3-MT) and normetanephrine (NM) in mesencephalon-pons, diencephalon, corpus striatum and hippocampus of rat brain were investigated. Effects of(More)
OBJECTIVES To validate a new functional assessment tool, the Goal Processing Scale (GPS), and to apply it for testing for sources of dysfunction in patients with acquired brain injury. Determining which component processes of executive functioning underlie poor performance in complex, low-structure settings would be valuable for the assessment of deficits(More)
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