Ryan M. Schweller

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Over the past several decades, there has been an ever-increasing demand for organ transplants. However, there is a severe shortage of donor organs, and as a result of the increasing demand, the gap between supply and demand continues to widen. A potential solution to this problem is to grow or fabricate organs using biomaterial scaffolds and a person's own(More)
The effects of mechanical cues on cell behaviors in 3D remain difficult to characterize as the ability to tune hydrogel mechanics often requires changes in the polymer density, potentially altering the material's biochemical and physical characteristics. Additionally, with most PEG diacrylate (PEGDA) hydrogels, forming materials with compressive moduli less(More)
Materials that support the assembly of new vasculature are critical for regenerative medicine. Controlling the scaffold’s mechanical properties may help to optimize neovascularization within implanted biomaterials. However, reducing the stiffness of synthetic hydrogels usually requires decreasing polymer densities or increasing chain lengths, both of which(More)
RESULTS: Out of 150 patients in the database, 50 (33.3% response rate) patients completed the survey. Fractures were 20% closed, 20% Gustilo-Anderson (GA) II, 40% GA-IIIa, and 20% GA-IIIb. Soft tissue reconstruction was local in 62% of patients while 38% of patients required free tissue transfer. Three patients required amputation for chronic osteomyelitis(More)
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