Ryan M Gonterman

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The purpose of this study was to evaluate the role of the epidermal growth factor receptor (EGFR) in parathyroid hormone-related protein (PTHrP) expression and humoral hypercalcaemia of malignancy (HHM), using two different human squamous-cell carcinoma (SCC) xenograft models. A randomised controlled study in which nude mice with RWGT2 and HARA xenografts(More)
Parathyroid hormone-related protein (PTHrP) is the causative factor of the paraneoplastic syndrome humoral hypercalcemia of malignancy (HHM) and it also contributes to osteolytic metastases, both of which are common complications of squamous carcinomas of the lung. Inhibition of autocrine epidermal growth factor receptor (EGFR) signaling has been shown to(More)
In developing organs, parathyroid hormone (PTH)/parathyroid hormone-related protein (PTHrP) receptor (PPR) signaling inhibits proliferation and differentiation of mesenchyme-derived cell types resulting in control of morphogenic events. Previous studies using PPR agonists and antagonists as well as transgenic overexpression of the PPR ligand PTHrP have(More)
The purpose of this study was to examine the relationship of the teaching method used with cognitive learning and learning retention outcomes of nurses when instructed in Imogene King's Theory of Goal Attainment. This study's quantitative, quasi-experimental design examined relationships and/or differences between variables or groups. Cognitive learning and(More)
A quality improvement program designed to facilitate the administration, tracking, and documentation of blood products and volume expanders resulted in improved patient safety, improved efficiency, more accurate documentation, and enhanced resource management. Key to the success of the program were the Transfusion Administration Record, the blood product(More)
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