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OBJECTIVE To correlate the quantitated tumor vascularity of implanted murine tumors as depicted by contrast-enhanced sonography with estimates made with magnetic resonance imaging and with estimates of the percentage of viable (metabolically active) tumor as depicted by fluorodeoxyglucose autoradiography. METHODS Implanted tumors in 10 mice were imaged(More)
BACKGROUND Behavioral assessment of mutant mouse models and novel candidate drugs is a slow and labor intensive process. This limitation produces a significant impediment to CNS drug discovery. NEW METHOD By combining video and vibration analysis we created an automated system that provides the most detailed description of mouse behavior available. Our(More)
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