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Cell behavior during endocardial to mesenchymal transition (EMT) was simulated using the cellular Potts formalism in Compucell 3D. The processes of loss of endocardial cohesion and invasion into the extracellular matrix (ECM) were stimulated by changing surface energy parameters. The simulations match in vitro results which suggest that endocardial motility(More)
A reflection-mode photoplethysmographic (rPPG) patch probe has been researched to improve its performance for non-invasive physiological assessment through electrically conductive adhesives (ECAs) based manufacture processes. Special PiN photodiodes and Light Emitting Diodes (LEDs) were mounted on a flexible printed circuit to reach the objectives of both(More)
This paper provides a first description of a multiscale systems modeling approach applied to the congenital birth defect known as the tetralogy of Fallot. The multiscale approach adopted owes a lot to the effort of the world-wide physiome consortium and the work of research groups within the European Union on the Virtual Physiological Human. Both a spatial(More)
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