Ruurd M. van Elburg

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We aimed to determine the effects of enteral supplementation of a prebiotic mixture of neutral and acidic oligosaccharides (scGOS/lcFOS/pAOS) on the faecal microbiota and microenvironment in preterm infants. Furthermore, we determined the influence of perinatal factors on the development of the faecal microbiota. In a randomised controlled trial, preterm(More)
Short-term supplementation of non-human neutral and acidic oligosaccharides during the first postnatal weeks may enhance the maturation of the immune response in preterm infants and may lead to less allergic and infectious diseases during the first year of life. In a randomized controlled trial, 113 preterm infants (gestational age <32 weeks and/or birth(More)
Background: Maternal antibodies, transported through the placenta during pregnancy, contribute to the protection of infants from infectious diseases during the first months of life. The aim of this study was to measure the concentration of antibodies against several vaccine-preventable diseases in paired maternal and cord blood serum samples in preterm and(More)
Introduction: Preterm infants have a delayed intestinal colonization. Supplementation of immune modulatory fibers to their diet can increase the production of beneficial shortchain-fatty acids profiles (SCFA) by intestinal microbes. The aims of this ex-vivo study were to determine: (1) capability of stool microbiota of premature infants to produce SCFA and(More)
Mechanical ventilation (MV) and ventilator strategies can induce or aggravate lung injury and may contribute to the development of distant organ failure, including the gastrointestinal tract. A retrospective cohort study was performed among 61 preterm infants, with a gestational age of 25-36 weeks, admitted at a neonatal intensive care unit. Intestinal(More)
Affiliations VU University Amsterdam, Department of Clinical Neuropsychology, Amsterdam, The Netherlands VU University Medical Center, Department of Physics and Medical Technology, Amsterdam, The Netherlands VU University Medical Center, Department of Pediatrics, Amsterdam, The Netherlands VU University Medical Center, Department of Pediatric Neurology,(More)
OBJECTIVE Routine obstetric ultrasound increasingly leads to the detection of structural fetal anomalies. In twin pregnancies with one anomalous twin, counseling on management strategies is complicated. PATIENTS AND METHODS Twin pregnancies (n = 212) were referred to a tertiary center between January 2007 and July 2009. In a retrospective analysis, twins(More)
Background: Maternal antibodies, transported over the placenta during pregnancy, contribute to the protection of infants from infectious diseases during the first months of life. In term infants, this protection does not last until the first recommended measles-mumpsrubella vaccination at 14 months in the Netherlands, while these viruses still circulate.(More)
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