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Microarray analysis of retinal gene expression in Egr-1 knockout mice

• Ruth Schippert, Frank Schaeffel, Marita Pauline Feldkaemper
• Molecular vision
• 2009

PURPOSE We found earlier that 42 day-old Egr-1 knockout mice had longer eyes and a more myopic refractive error compared to their wild-types. To identify genes that could be responsible for the… (More)

Peripheral defocus does not necessarily affect central refractive development

• Ruth Schippert, Frank Schaeffel
• Vision Research
• 2006

PURPOSE Recent experiments in monkeys suggest that deprivation, imposed only in the periphery of the visual field, can induce foveal myopia. This raises the hypothesis that peripheral refractive… (More)

Microarray analysis of retinal gene expression in chicks during imposed myopic defocus

• Ruth Schippert, Frank Schaeffel, Marita Pauline Feldkaemper
• Molecular vision
• 2008

PURPOSE The retina plays an important regulatory role in ocular growth. To screen for new retinal candidate genes that could be involved in the inhibition of ocular growth, we used chick microarrays… (More)

Relative axial myopia in Egr-1 (ZENK) knockout mice.

• Ruth Schippert, Eva Burkhardt, Marita Pauline Feldkaemper, Frank Schaeffel
• Investigative ophthalmology & visual science
• 2007

PURPOSE Experiments in chickens have implicated the transcription factor ZENK (also known as Egr-1, NGFI-A, zif268, tis8, cef5, and Krox24) in the feedback mechanisms for visual control of axial eye… (More)

Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations

• Katarína Stingl, Ruth Schippert, +17 authors Eberhart Zrenner
• Front. Neurosci.
• 2017

Purpose: We assessed the safety and efficacy of a technically advanced subretinal electronic implant, RETINA IMPLANT Alpha AMS, in end stage retinal degeneration in an interim analysis of two ongoing… (More)

Changes in scleral MMP-2, TIMP-2 and TGFbeta-2 mRNA expression after imposed myopic and hyperopic defocus in chickens.

• Ruth Schippert, Christine Brand, Frank Schaeffel, Marita Pauline Feldkaemper
• Experimental eye research
• 2006

Induction of myopia leads to a decreased glycosaminoglycan synthesis and smaller collagen fibrillar diameters, increased levels of gelatinase-A (MMP-2) and decreased amounts of tissue inhibitor of… (More)

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