Ruth L. Savage

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It is well established that variations in genes can alter the pharmacokinetic and pharmacodynamic profile of a drug and immunological responses to it. Early advances in pharmacogenetics were made with traditional genetic techniques such as functional cloning of genes using knowledge gained from purified proteins, and candidate gene analysis. Over the past(More)
This paper reports the experimental demonstration of frequency upshifting of microwave radiation by a relativis-tic ionization front. Source radiation at 34.8 GHz has been upshifted to greater than 116 GHz in a continuously tunable fashion. It is a new technique for generating high-power, tun-able radiation in short pulses, and has potential applications in(More)
In the online published article Section 3, para 2, lines 4–5, which previously read: …Gordon et al. applied targeted NGS of multiple genes from over 14,000 subjects, to illustrate the extent of potentially… Should read: …Gordon et al. applied targeted NGS of multiple genes from 6503 subjects, to illustrate the extent of potentially… The online version of(More)
When pulse of electromagnetic radiation impinges upon a moving plasmalneutral gas boundary, i.e., an ioniza-tion front, its frequency and duration are altered. The largest frequency upshifts and pulse compressions are obtained when radiation is incident on an ionization front moving at close to the speed of light. Such an ionization front is created when a(More)
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