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OBJECTIVES Despite the growing number of pharmacoeconomic (PE)/health economic (HE) studies, very little is known about their use by decision makers. The objectives of the Task Force were to ensure that the good research practices of PE/HE studies pay attention to the needs of health-care decision makers and to develop a "toolbox" for the health-care(More)
STUDY OBJECTIVE Good communication is important in patient care and plays an essential part of teamwork and patient safety. Communication in the emergency department (ED) can be chaotic, with the potential for error resulting from communication overload and problems of communication. The nurse in charge of the ED plays a crucial role in maintaining(More)
INTRODUCTION The objective of this study was to report the impact of exacerbations on health-related quality of life (HRQL) and health utility in patients with moderate to severe asthma (BTS levels 4 & 5) in the UK. MATERIALS AND METHODS Prospective data regarding HRQL were collected (n=112) using the EQ-5D, mini Asthma Quality of Life Questionnaire(More)
BACKGROUND Although the link between cannabis use and development of psychosis is well established, less is known about the effect of continued versus discontinued cannabis use after the onset of psychosis. We aimed to summarise available evidence focusing on the relationship between continued and discontinued cannabis use after onset of psychosis and its(More)
OBJECTIVES A growing number of prospective clinical trials include economic end points. Recognizing the variation in methodology and reporting of these studies, the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) chartered the Task Force on Good Research Practices: Randomized Clinical Trials-Cost-Effectiveness Analysis. Its goal(More)
BACKGROUND Communication in the emergency department (ED) is a complex process where failure can lead to poor patient care, loss of information, delays and inefficiency. AIM To describe the investigation of the communication processes within the ED, identify points of vulnerability and guide improvement strategies. METHODS The Failure Mode Effects(More)
BACKGROUND Diagnostic error is a significant problem in emergency medicine, where initial clinical assessment and decision making is often based on incomplete clinical information. Traditional computerised diagnostic systems have been of limited use in the acute setting, mainly due to the need for lengthy system consultation. We evaluated a novel web-based(More)
OBJECTIVE A head-to-head comparator study has shown that the clinical efficacy of ustekinumab is superior to that of etanercept over a 12-week period in patients with psoriasis. Economic models are often hindered by the lack of trials directly comparing outcomes between relevant alternative therapies. The aim of this analysis was to evaluate the(More)
Prior alert via a landline telephone ("blue call") is commonly used to warn accident and emergency (A&E) departments of the impending arrival of a seriously ill or injured patient. There are no published indications for making such calls or validated protocols on message content. Submitted telephone information has the potential for distortion as it is(More)
In this article we show how an interpretative methodology of narrative analysis is beneficial for the study of public administration. We demonstrate the use and usefulness of a method for analyzing narratives that is based in concepts from classical rhetoric and semiotics. The method allows researchers to make more available the unstated, implicit(More)