Ruth Ann Miles

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OBJECTIVE To determine pharmacokinetic and endometrial effects of vaginally delivered micronized P. DESIGN Functionally agonadal estrogen-replacement recipients received either micronized P administered vaginally or bi-daily IM injections of P. Hourly blood samples were obtained, from baseline to 6 hours after the initial dose of P and again on simulated(More)
OBJECTIVES To determine the efficacy of grade 4 cystocele repair using the four-defect repair (FDR) or modified FDR with porcine xenograft matrix (FDR+Pelvicol). METHODS During a 4-year period, 45 women underwent grade 4 cystocele repair. Of the 45 patients, 43 (95.5%) were available for follow-up. The mean age was 65 years. Patients presented with the(More)
OBJECTIVE We report our experience with laparoscopic donor nephrectomy (LDN) in the setting of complex renal vasculature and critically analyze the technique and intermediate recipient outcomes. METHODS Thirty-nine living renal donors with multiple renal arteries or veins, or anomalous venous anatomy, who underwent LDN between 2003 and 2007 at our(More)
OBJECTIVE Assessment of an in vivo test for 5 alpha-reductase activity using serum markers, 5 alpha-androstane-3 alpha,17 beta-diol glucuronide and androsterone glucuronide, after the cutaneous application of androstenedione (A). DESIGN An A gel was applied for 6 days to the skin of normal women, male volunteers, and hirsute and nonhirsute patients with(More)
OBJECTIVE To determine if the ratio of serum androstenedione (A):11 beta-hydroxyandrostenedione (OHA) would be helpful in differentiating adrenal from ovarian hyperandrogenism. DESIGN/SETTING Prospective study of outpatients being evaluated for hyperandrogenism. PATIENTS/PARTICIPANTS Normal women (n = 27), those with hyperandrogenic chronic anovulation(More)
All antigens (leishmanin) prepared from nine isolates of Leishmania gave positive skin tests in guinea pigs infected with L. enriettii. However, variation in potency was observed and ascribed to batch variation. It is recommended that biological testing of leishmanin is considered before use in field surveys or as an aid to clinical diagnosis.