Ruth A Prescott

Learn More
METHOD A systematic review of three bibliographic databases from 1986 to 1996 identified 78 papers reporting barriers to recruitment of clinicians and patients to randomised controlled trials. RESULTS Clinician barriers included: time constraints, lack of staff and training, worry about the impact on the doctor-patient relationship, concern for patients,(More)
BACKGROUND Although the cytolytic, neurotoxic, and hemolytic actions of snake venoms are well known, the ability of airborne inhaled snake venom of the spitting cobra to induce asthma in snake handlers has not been reported. OBJECTIVE To report the allergenicity of inhaled snake venom in a snake handler who developed increasing hypersensitivity to(More)
BACKGROUND Chronic urticaria (CU) in childhood remains a challenge for investigation, and its etiology is largely unknown. Autoantibodies to the high-affinity IgE receptor (FcepsilonRI) are believed to play a role in the pathogenesis of this disease in adults. OBJECTIVE To determine the prevalence of autoantibodies to FcepsilonRIalpha on basophils in(More)
BACKGROUND In the subtropical climate of South Africa, grasses of the subfamily Panicoideae are predominant. Bermuda grass has previously been shown to be an important local allergen, and immunoglobulin E (IgE) epitopes of Bermuda grass extracts are known to be distinct from those of the Pooid pollen extracts. Following our demonstration of sensitivity in(More)
OBJECTIVE To determine the levels of the allergen DerPI, attributable to the house-dust mite (HDM) Dermatophagoides pteronyssinus. DESIGN A four-season study conducted during 1994/95, sampling mattresses and carpets in the main bedrooms of suburban homes. SETTING Thirty randomly selected homes in the Edenvale area, occupied by both black and white(More)
BACKGROUND Relatively little attention has been paid to rye flour as opposed to wheat flour in clinical and epidemiological research into Baker's asthma. METHODS This report describes the investigation of a baker with asthma who reported a workplace response to rye flour and none to wheat flour, despite co-reactivity to both wheat and rye antigen. (More)