Rutger C. Zietsma

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OBJECTIVE To assess whether standardized handwriting can provide quantitative measures to distinguish patients diagnosed with Parkinson's disease from age- and gender-matched healthy control participants. DESIGN Exploratory study. Pen tip trajectories were recorded during circle, spiral and line drawing and repeated character 'elelelel' and sentence(More)
Neurodegeneration in Parkinson's disease (PD) affects both the fine motor control of the fingers and gross movement of the upper limb. Handwriting examinations are commonly performed in the analysis of tremor in PD and there is validity in subjective assessment in the clinic. However, there is clinical need for a more objective assessment instrument to(More)
The most widely used method to assess motor functioning in Parkinson's disease (PD) patients is the unified Parkinson's disease rating scale-III (UPDRS-III). The UPDRS-III has limited ability to detect subtle changes in motor symptoms. Alternatively, graphical tasks can be used to provide objective measures of upper limb motor dysfunction.(More)
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