Rusty Williams

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Metformin is an oral hypoglycemic drug that has been shown to inhibit cancer cell proliferation via up-regulation of AMPK (AMP-activated protein kinase), and possibly inhibition of mTOR (mammalian target of rapamycin). The purpose of this study was to evaluate the effects of metformin on a feline injection site sarcoma cell line. Cells from a feline(More)
s: Session III 8 1 tissues, but at tenfold lower levels than in prostate. The only prostate cancer cell line that expresses 1B10 is an androgen-sensitive cell line, LNCaP, suggesting that the gene might be androgen-regulated. Cloning of the full-length cDNA has so far resulted in 4.6 kb of the transcript. The 3′ end of the coding region is significantly(More)
Various buffers (0.2 M acetate, pH 4.2; 0.01 M phosphate with 0.15 M sodium chloride, pH 7.2; 0.15 M borate, pH 8.2 and 0.025 M carbonate, pH 9.6) were used as coating buffers with Brucella abortus alkali treated lipopolysaccharide on two types of plastic matrices. Maximum binding occurred using the phosphate buffer. However, as was the case with the other(More)
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