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It has been suggested that the hippocampal theta rhythm can contribute to memory formation by separating encoding and retrieval of memories into different functional cycles [1]. Herein, we investigate via computer simulations the mechanisms by which storage of spatio-temporal input patterns is achieved by the CA1 microcircuitry. A model of the CA1(More)
Overview The hippocampal regions CA3 and CA1 have long been proposed to be auto-, for the storage of declarative information. An autoassociative memory is formed when a set of neurons are recurrently connected by modifiable synapses, whereas a heteroassociative memory is formed through modifiable connections from an input layer of neurons to an output(More)
Introduction Similarities between neural network models of associative memory and the mammalian hippocampus have been examined [1,2]. Here we compare and contrast the recall dynamics and quality of a biologically based spiking network [3] which is comprised of 1000 biologically realistic Pinsky-Rinzel two-compartment model CA3 pyramidal cells [4] with the(More)
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