Russell H Murdock

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The Animal Models for Protecting Ischemic Myocardium Study was undertaken for the purpose of developing reproducible animal models that could be used to assess interventions designed to limit infarct size. This paper describes the results obtained in an unconscious dog model and in a conscious dog model, developed in three participating laboratories. The(More)
Some field tests in counter-terrorism efforts to detect explosive traces employ chemistries that yield colored products. We have examined a test kit of this kind, ETK(Plus), based on widely used chemistries and employed extensively by the Israel Police. Our investigation focuses on the prospect of gaining sensitivity by replacing the normal colorimetric(More)
BACKGROUND & AIMS Azathioprine is effective for Crohn's disease but acts slowly. A loading dose may decrease the time to response. METHODS A placebo-controlled study was conducted in patients with active Crohn's disease despite prednisone treatment. Patients were randomized to a 36-hour infusion of azathioprine, 40 mg/kg (51 patients), or placebo (45(More)
to regional myocardial perfusion. Circulation 51: 641, 1975 12. Bradley-Moore PR, Lebowitz E, Greene MW, Atkins HL, Ansari AN: Thallium-201 for medical use. II. Biologic behavior. J Nucl Med 16: 156, 1975 13. Beller GA, Watson DD, Pohost GM: Kinetics of thallium distribution and redistribution: clinical applications in sequential myocardial imaging. In(More)
The present study evaluates the transitional or border zone of intermediate blood flow reduction between nonischemic and ischemic regions after acute coronary artery occlusion in chronically instrumented dogs, using methods that minimize an admixture of ischemic and nonischemic myocardium in the tissue analyzed. The regions perfused by occluded and(More)
BACKGROUND Many otherwise healthy individuals with episodic heartburn self-medicate with over-the-counter antacids. We evaluated clinical characteristics of subjects who had never been medically diagnosed as having any upper gastrointestinal tract disorder and who used antacids for symptomatic relief of heartburn. SUBJECTS AND METHODS Subjects with at(More)
BACKGROUND Ranitidine 150 mg q.d.s. is the currently recommended dosage in the United States for the treatment of erosive oesophagitis. To determine whether a higher dose of ranitidine administered less frequently would also be effective in healing erosive oesophagitis, we compared ranitidine 300 mg b.d. with ranitidine 150 mg q.d.s. in the treatment of(More)
BACKGROUND Many individuals with heartburn self-medicate with antacids for relief of their symptoms. AIM To compare efficacy of effervescent ranitidine to as-needed calcium carbonate antacids in subjects who self-treat heartburn. METHODS A total of 155 subjects with frequent antacid-responsive heartburn were randomized to receive effervescent ranitidine(More)
Two ranitidine dosages were compared for the treatment of erosive esophagitis in a multicenter, double-blind, randomized, parallel-group, placebo-controlled study. Adults with endoscopically verified erosive esophagitis were treated with either ranitidine 150 mg four times daily (n = 106), ranitidine 300 mg four times daily (n = 106), or placebo (n = 116)(More)
CdS/dendrimer nanocomposites with a range of concentrations of the photoluminescent semiconductor nanocluster and the dendrimer are prepared in methanol and 1:9 methanol:water solutions. The solutions are utilized for detection of cyanoacrylate ester fumed and unfumed fingerprints on polyethylene and aluminum foil.