• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage your publications. Semantic Scholar automatically creates author pages based on data aggregated from public sources and our publisher partners.
  • Charles A. Jr. Janeway, Ruslan Medzhitov
  • Medicine, Biology
  • Annual review of immunology
  • 2002 (First Publication: 1 April 2002)
  • The innate immune system is a universal and ancient form of host defense against infection. Innate immune recognition relies on a limited number of germline-encoded receptors. These receptors evolvedContinue Reading
  • Ruslan Medzhitov
  • Medicine, Biology
  • Nature Reviews Immunology
  • 2001 (First Publication: 1 November 2001)
  • Toll-like receptors have a crucial role in the detection of microbial infection in mammals and insects. In mammals, these receptors have evolved to recognize conserved products unique to microbialContinue Reading
  • Seth Rakoff-Nahoum, Justin C Paglino, Fatima Eslami-Varzaneh, Stephen C. Edberg, Ruslan Medzhitov
  • Medicine, Biology
  • Cell
  • 2004 (First Publication: 1 July 2004)
  • Toll-like receptors (TLRs) play a crucial role in host defense against microbial infection. The microbial ligands recognized by TLRs are not unique to pathogens, however, and are produced by bothContinue Reading
  • Jennifer M. Lund, Ayuko Sato, Shizuo Akira, Ruslan Medzhitov, Akiko Iwasaki
  • Medicine, Biology
  • The Journal of experimental medicine
  • 2003 (First Publication: 4 August 2003)
  • Plasmacytoid dendritic cells (pDCs) have been identified as a potent secretor of the type I interferons (IFNs) in response to CpG as well as several viruses. In this study, we examined the molecularContinue Reading