Rupert Laurenz Mayer

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Polyphenol oxidase (PPO) is a type-3 copper enzyme catalyzing the oxidation of phenolic compounds to their quinone derivates, which are further converted to melanin, a ubiquitous pigment in living organisms. In this study a plant originated tyrosinase was isolated from walnut leaves (Juglans regia) and biochemically characterized. It was possible to isolate(More)
A series of protein kinases and phosphatases (PKPs) have been linked to contextual fear conditioning (cFC) but information is mainly derived from immunochemical studies. It was therefore decided to use an explorative label-free quantitative proteomics approach to concomitantly determine PKPs in hippocampi of mice in the individual phases of cFC. C57BL/6J(More)
Aurone synthase belongs to the novel group 2 polyphenol oxidases and the presented kinetic characterization suggests a differing aurone biosynthesis in Asteraceae species compared to snapdragon. Aurone synthases (AUS) are polyphenol oxidases (PPO) physiologically involved in the formation of yellow aurone pigments in petals of various Asteraceae species.(More)
Aurone synthase from Coreopsis grandiflora (cgAUS1), catalyzing conversion of butein to sulfuretin in a type-3 copper center, is a rare example of a polyphenol oxidase involved in anabolism. Site-directed mutagenesis around the CuA site of AUS1 was performed, and recombinant enzymes were analyzed by mass spectrometry. Replacement of the coordinating CuA(More)
Fear of dental treatment is undoubtedly widespread. In the present study this fear, the "stress phenomenon", has been investigated. So-called biosignals were used to demonstrate the factual presence of these "anxiety conditions"; it has been found that they are increasing at the beginning of treatment and reach peak levels during certain much feared(More)
Hygienic studies of the manual buttons of a modern dental unit show that these buttons are being contaminated during treatment. The number of germs depends on the duration of treatment and on the number of patients treated. As these buttons were pushed with the foot in dental chairs of older design, the ergonomic advantages of modern dental units do not(More)
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