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Current speech synthesis technology is difficult to understand in everyday noise situations. Although there is a significant body of work on how humans modify their speech in noise, the results have yet to be implemented in a synthesizer. Algorithms capable of processing and incorporating these modifications may lead to improved speech intelligibility of(More)
OBJECTIVE Sphingosylphosphorylcholine (SPC) is an important lipid mediator that has been implicated in vascular disease. As it has not been studied in the pulmonary circulation, we examined its mechanisms of action in rat small intrapulmonary arteries (IPA). METHODS IPA were mounted on a myograph for recording tension and intracellular Ca2+ concentration(More)
The Human Speechome Project is an effort to observe and computationally model the longitudinal course of language development for a single child at an unprecedented scale. The idea is this: Instrument a child's home so that nearly everything the child hears and sees from birth to three is recorded. Develop a computational model of language learning that(More)
PURPOSE The Lombard effect describes the tendency for speakers to increase pitch, intensity, and duration in the presence of noise. It is unclear whether these modifications are uniformly applied across all words within an utterance or whether information-bearing content words are further enhanced compared with function words. In the present study, the(More)
  • Rupal Patel
  • 2002
Speakers with severe dysarthria are known to have reduced range in prosody. Consistent control within that range, however, has largely been ignored. In earlier investigations speakers with severe dysarthria were able to control pitch and duration for sustained vowel production despite reduced flexibility of control (Patel, 1998). The present experiment(More)
UNLABELLED Splenosis is a rare finding of ectopic splenic tissue found within the thoracic cavity, abdomen or peritoneal cavity. Most cases occur in the abdomen and the thoracic location is a comparatively rare finding. In thoracic splenosis the splenic tissue most often grows in the form of a nodule and the autotransplantation is usually caused by a(More)
BACKGROUND Isolated patellofemoral joint osteoarthritis affects approximately 10% of patients aged over 40 years and treatment remains controversial. The Femoro Patella Vialli (FPV) patellofemoral joint replacement (Wright Medical Technology, UK) has been shown to restore functional kinematics of the knee close to normal. Despite its increasing popularity(More)
Does consuming more goods make people happier? For a broad spectrum of goods, available evidence suggests that beyond some point the answer is essentially no. Much of this evidence is from the large and growing scientific literature on the determinants of life-satisfaction and psychological well-being. 1 Evidence from this literature also suggests, however,(More)
PURPOSE To determine relevant demographics, clinical features, and outcomes for septic arthritis in patients on haemodialysis for end-stage renal failure. METHODS A multi-centre retrospective review was performed from 1999 to 2005. RESULTS 15 cases were identified. The mean age of the patients at diagnosis was 67 (range, 23-89) years and 11 were male.(More)