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Cannabinoids as novel anti-inflammatory drugs.
- P. Nagarkatti, Rupal Pandey, S. Rieder, V. Hegde, M. Nagarkatti
- BiologyFuture medicinal chemistry
- 21 October 2009
This review will focus on the potential use of cannabinoids as a new class of anti-inflammatory agents against a number of inflammatory and autoimmune diseases that are primarily triggered by activated T cells or other cellular immune components.
Targeting Cannabinoid Receptors as a Novel Approach in the Treatment of Graft-versus-Host Disease: Evidence from an Experimental Murine Model
- Rupal Pandey, V. Hegde, M. Nagarkatti, P. Nagarkatti
- Biology, MedicineJournal of Pharmacology and Experimental…
- 1 September 2011
The ability of THC to reduce the clinical GVHD was reversed, at least in part, by administration of cannabinoid receptor (CB) 1 and CB2 antagonists, thereby demonstrating that THC-mediated amelioration of GV HD was cannabinoid receptor-dependent.
Endocannabinoids and immune regulation.
Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis.
BK channel activation with NS1619 decreases excitability and contractility of human urinary bladder smooth muscle