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The anabolic steroid oxandrolone is increasingly used to preserve or restore muscle mass in those with HIV infection or serious burns. These effects are mediated, in part, by the androgen receptor (AR). Anti-glucocorticoid effects have also been reported for some anabolic steroids, and the goal of our studies was to determine whether oxandrolone had a… (More)
Neuroblastoma (NB) is the most common extracranial solid tumor in children. NB tumors and derived cell lines are phenotypically heterogeneous. Cell lines are classified by phenotype, each having distinct differentiation and tumorigenic properties. The neuroblastic phenotype is tumorigenic, has neuronal features and includes stem cells (I-cells) and neuronal… (More)
J o u r n a l o f P r o b a b i l i t y Electron. Abstract For normally reflected Brownian motion and for simple random walk on independently growing in time d-dimensional domains, d ≥ 3, we establish a sharp criterion for recurrence versus transience in terms of the growth rate.
An algorithm for solving continuous-time stochastic optimal control problems is presented. The numerical scheme is based on the stochastic maximum principle (SMP) as an alternative to the widely studied dynamic programming principle (DDP). By using the SMP, (Peng, 1990) obtained a system of coupled forward-backward stochastic differential equations (FBSDE)… (More)
We consider recurrence versus transience for models of random walks on growing in time, connected subsets Gt of some fixed locally finite, connected graph, in which monotone interaction enforces such growth as a result of visits by the walk (or probes it sent), to the neighborhood of the boundary of Gt.