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- Mohammed Merza, Hannes Hartman, +7 authors Henrik Thorlacius
- Gastroenterology
- 2015
BACKGROUND & AIMS
Neutrophils are involved in the development of acute pancreatitis (AP), but it is not clear how neutrophil-induced tissue damage is regulated. In addition to secreting antimicrobial… (More)
- Rundk Hwaiz, Milladur Rahman, Enming Zhang, Henrik Thorlacius
- British journal of pharmacology
- 2015
BACKGROUND AND PURPOSE
Platelets are potent regulators of neutrophil accumulation in septic lung damage. We hypothesized that platelet-derived CXCL4 might support pulmonary neutrophilia in a murine… (More)
- Rundk Hwaiz
- 2015
- Rundk Hwaiz, Zirak Hasan, +5 authors Henrik Thorlacius
- The Journal of surgical research
- 2013
Excessive neutrophil recruitment is a major feature in septic lung damage although the signaling mechanisms behind pulmonary infiltration of neutrophils in sepsis remain elusive. In the present… (More)
- Zirak Hasan, Karzan Palani, +6 authors Henrik Thorlacius
- Infection and immunity
- 2013
T-cell dysfunction increases susceptibility to infections in patients with sepsis. In the present study, we hypothesized that Rho kinase signaling might regulate induction of T-cell dysfunction in… (More)
- Rundk Hwaiz, Milladur Rahman, I Syk, Enming Zhang, Henrik Thorlacius
- Journal of leukocyte biology
- 2015
Accumulating evidence suggest that platelets play an important role in regulating neutrophil recruitment in septic lung injury. Herein, we hypothesized that platelet-derived CCL5 might facilitate… (More)
- Mohammed Merza, Milladur Rahman, +4 authors Henrik Thorlacius
- American journal of physiology. Gastrointestinal…
- 2014
Severe acute pancreatitis (AP) is characterized by leukocyte infiltration and tissue injury. Herein, we wanted to examine the potential effects of thrombin-derived host defense peptides (TDPs) in… (More)
- Songen Zhang, Rundk Hwaiz, Milladur Rahman, Heiko Herwald, Henrik Thorlacius
- European journal of pharmacology
- 2014
Streptococcal toxic shock syndrome (STSS) is associated with a high mortality rate. The M1 serotype of Streptococcus pyogenes is most frequently associated with STSS. Herein, we examined the role of… (More)
- Songen Zhang, Rundk Hwaiz, Lingtao Luo, Heiko Herwald, Henrik Thorlacius
- American journal of physiology. Lung cellular and…
- 2015
Streptococcus pyogenes cause infections ranging from mild pharyngitis to severe streptococcal toxic shock syndrome (STSS). The M1 serotype of Streptococcus pyogenes is most frequently associated with… (More)
- Changhui Yu, Su Lei Zhang, +4 authors Henrik Thorlacius
- European journal of pharmacology
- 2014
Excessive neutrophil recruitment in the colon is a major feature in acute colitis although the signaling mechanisms behind colonic recruitment of neutrophils remain elusive. Herein, we hypothesized… (More)