Ruixue Duan

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Pancreatic β cell dysfunction and reduction due to glucose toxicity play a crucial role in the development of type 2 diabetes mellitus (T2DM). Irisin, a novel exercise-induced myokine, reduces obesity, improves insulin resistance and lowers blood glucose by promoting the browning of white adipose tissue, thereby enhancing thermogenesis and increasing energy(More)
The prospect of applying differentiation therapies to the treatment of acute myeloid leukemias (AMLs) is highlighted by the use of all-trans retinoic acid (ATRA) in acute promyelocytic leukemia (APL). Treatment with ATRA in combination with chemotherapy or arsenic trioxide results in cure in the majority of patients with either newly diagnosed or recurrent(More)
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