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PURPOSE The objective of this trial was to compare two vinorelbine-based doublets with carboplatin (CBDCA-VC) or with gemcitabine (VG) in patients with stage IIIB-IV non-small cell lung cancer (NSCLC). PATIENTS AND METHODS A total of 316 patients with advanced NSCLC previously untreated were randomized to either vinorelbine 30 mg/m(2) D1,8 with(More)
OBJECTIVES Peripheral arterial disease (PAD) is associated with morbidity and mortality of coronary heart disease and stroke. Hypertension is an independent risk factor for peripheral arterial disease. However, the prevalence and risk factors of PAD in hypertensive patients have not been studied in China. METHODS In order to investigate the prevalence of(More)
A patient with a 25-year history of recurrent left nasal polyps is described. Recurrent papillomatosis (schneiderian or inverted papilloma) involving the left nasal cavity had been histologically documented for five years. Following the onset of and chemotherapy for acute myelomonocytic leukemia, the patient developed papillomatosis in the right nasal(More)
Venous air embolism is a potentially serious complication of neurosurgery that occurs more commonly when the patient is in the sitting position. In this study, we aimed to quantify the incidence of venous air embolism during neurosurgical procedures performed with the patient in the sitting position in our institution. We performed a prospective audit of(More)
Laryngeal arthritis is a rare manifestation of JRA. The difficulty of indirect laryngoscopy in small children has precluded the type of study which has demonstrated this manifestation in up to one quarter of arthritic adults. Recognition of cricoarytenoid arthritis in the patient reported might have prevented the need for tracheostomy, and eventually led to(More)
OBJECTIVE Low-density lipoproteins (LDL) are a heterogeneous group of particles, with small, dense particles being more atherogenic. It remains controversial whether elevated plasma levels of small dense LDL (sd-LDL) are risk factors for stroke. The aim of the present study was to examine the plasma levels of sd-LDL in patients with stroke and to(More)
This retrospective non-randomized study reports the outcome of 67 patients who received radical radiotherapy with or without two courses of concomitant chemotherapy using 5-fluorouracil and cis-platin at Westmead Hospital from 1985 to 1992. The overall median survival was 14.0 months, the actuarial 5-year survival was 18%, and median disease-free survival(More)
7016 Background: NVB-CDDP is used as a standard regimen for pts with NSCLC. Regimens in which CDDP is replaced by CBDCA or a non Platinum (P) cytotoxic, may result in more favourable tolerance and convenience This phase III was set up to compare a P based regimen (NVB-CBDCA) to a non-P based regimen (NVB-GEM). METHODS Inoperable NSCLC pts were randomly(More)
e21023 Background: In some solid cancers a survival benefit has been observed for patients who had chemotherapy-induced neutropenia. The prognostic impact of baseline and nadir blood neutrophils was assessed in the present study. METHODS Data on patients with breast cancer st.I-IV, ovarian cancer st.I-IV, non-small cell lung cancer (NSCLC) st.II-IV, and(More)
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