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Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end product.

• Ruijin Zheng, Diane E. Heck, +5 authors Jeffrey D Laskin
• Toxicology and applied pharmacology
• 2014

4-Hydroxynonenal (4-HNE) is a lipid peroxidation end product generated in response to oxidative stress in the skin. Keratinocytes contain an array of antioxidant enzymes which protect against… (More)

Transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice.

• Joshua D. Lambert, Dou Hwan Kim, Ruijin Zheng, Chung S Yang
• The Journal of pharmacy and pharmacology
• 2006

Epigallocatechin-3-gallate (EGCG) is the most studied catechin in green tea (Camellia sinensis). EGCG and green tea are cancer preventive in many animal models, and numerous mechanisms have been… (More)

The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard.

• Ruijin Zheng, Iris P Po, +7 authors Jeffrey D Laskin
• Toxicology and applied pharmacology
• 2013

The cornea is highly sensitive to oxidative stress, a process that can lead to lipid peroxidation. Ultraviolet light B (UVB) and nitrogen mustard (mechlorethamine) are corneal toxicants known to… (More)

Differential metabolism of 4-hydroxynonenal in liver, lung and brain of mice and rats.

• Ruijin Zheng, Ana-Cristina Docan Dragomir, +4 authors Jeffrey D Laskin
• Toxicology and applied pharmacology
• 2014

The lipid peroxidation end-product 4-hydroxynonenal (4-HNE) is generated in tissues during oxidative stress. As a reactive aldehyde, it forms Michael adducts with nucleophiles, a process that… (More)

Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid.

• Ruijin Zheng, Diane E. Heck, Adrienne T Black, Andrew Gow, Debra L. Laskin, Jeffrey D Laskin
• Free radical biology & medicine
• 2014

Nitric oxide and various by-products including nitrite contribute to tissue injury by forming novel intermediates via redox-mediated nitration reactions. Nitration of unsaturated fatty acids… (More)

Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages

• Weishan Fang, Decheng Bi, +6 authors Xu Xu
• Scientific Reports
• 2017

Alginate, a natural acidic polysaccharide extracted from marine brown seaweeds, is composed of different blocks of β-(1, 4)-D-mannuronate (M) and its C-5 epimer α-(1, 4)-L-guluronate (G).… (More)

N-Doped Mesoporous In2 O3 for Photocatalytic Oxygen Evolution from the In-based Metal-Organic Frameworks.

• Xiaoyu Gan, Ruijin Zheng, +4 authors Xun Sun
• Chemistry
• 2017

As an excellent n-type semiconductor, indium oxide (In2 O3 ) is also a good candidate for photocatalysis such as light-induced water splitting. However, the efficiency of the oxygen evolution… (More)

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