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Re-annotation of presumed noncoding disease/trait-associated genetic variants by integrative analyses

• Geng Chen, Dianke Yu, +6 authors Tieliu Shi
• Scientific reports
• 2015

Using RefSeq annotations, most disease/trait-associated genetic variants identified by genome-wide association studies (GWAS) appear to be located within intronic or intergenic regions, which makes… (More)

dbSAP: single amino-acid polymorphism database for protein variation detection

• Ruifang Cao, Yan Shi, +5 authors Tieliu Shi
• Nucleic Acids Research
• 2017

Millions of human single nucleotide polymorphisms (SNPs) or mutations have been identified so far, and these variants could be strongly correlated with phenotypic variations of traits/diseases. Among… (More)

Identifying and annotating human bifunctional RNAs reveals their versatile functions

• Geng Chen, Juan Yang, +4 authors Leming Shi
• Science China Life Sciences
• 2016

Bifunctional RNAs that possess both protein-coding and noncoding functional properties were less explored and poorly understood. Here we systematically explored the characteristics and functions of… (More)

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