Rui-qing Chen

  • Citations Per Year
Learn More
OBJECTIVE To investigate the association between the heat shock protein 70-2 gene polymorphism and ankylosing spondylitis (AS). METHODS The polymorphisms of HSP70-2 gene Pst I 1267 site were analysed in 176 Chinese Han AS patients and 127 healthy controls by PCR and restriction fragment length polymorphisms(RFLP) methods. RESULTS In AS patients HSP70-2(More)
AIM To examine the effect of aberrant methylation of the KISS1 promoter on the development of colorectal cancer (CRC) and to investigate reversing aberrant methylation of the KISS1 promoter as a potential therapeutic target. METHODS KISS1 promoter methylation, mRNA expression and protein expression were detected by methylation-specific polymerase chain(More)
Cisplatin is a chemotherapeutic drug for treatment of many solid tumors. It has been shown to induce apoptosis and/or necrosis in different types of cancer cells. However, the underlying mechanisms remain elusive. In this study, we provide evidences that cisplatin induces necroptosis in receptor-interacting protein 3 (RIP3)-expressing cell lines, but not in(More)
OBJECTIVE To report a case of critical illness polyneuropathy (CIP) with Parkinson disease and discuss the development, clinical features and early diagnosis of this condition. METHODS The clinical data of a patient with CIP and Parkinson's disease and the relevant literature were reviewed. RESULTS This case showed no typical disease course of sepsis,(More)
  • 1