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Laboratories are increasingly requested to perform CYP2C19 genetic testing when managing clopidogrel therapy, especially in patients with acute coronary syndrome undergoing percutaneous coronary intervention. To ensure high quality molecular testing and ascertain that the referring clinician has the correct information for CYP2C19 genotype-directed(More)
Despite a large proportion of smoker in Chinese population, few studies address the prevalence of smoking in schizophrenia in such a homogeneous ethnic group. This study examined gender-specific relationships between smoking and schizophrenia, which have previously received little systematic study. The prevalence of smoking in 510 inpatients with(More)
BACKGROUND Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of pathogenic autoantibodies. Recent studies suggest that microRNAs (miRNAs) play an essential role in immunoregulation and may be involved in the pathogenesis of SLE. Therefore, it was of interest to investigate the potential therapeutic application(More)
—For many vehicular safety applications, it is critical to timely and reliably deliver multimedia data from a traveling vehicle to a roadside access point (AP) in an error-prone vehicular ad hoc network (VANET), which is a typical uplink scenario for drive-thru Internet. To achieve this goal, we propose a cooperative retransmission scheme that exploits a(More)
Although hepatocellular carcinoma (HCC) with bile duct tumor thrombus (BDTT) is a rare entity, most patients experience tumor recurrence even after curative resection and the prognosis remains dismal. This study aimed to analyze the clinicopathological risk factors for recurrence and poor outcome after surgical treatment of HCC with BDTT.(More)
Aging has been associated with mitochondrial DNA damage. P66Shc is an age-related adaptor protein that has a substantial impact on mitochondrial metabolism through regulation of the cellular response to oxidative stress. Our study aimed to establish a D-galactose (D-gal)-induced inner ear aging mouse model and to investigate the potential role of p66Shc and(More)
In this paper, a novel approach to texture retrieval using independent component analysis (ICA) in wavelet domain is proposed. It is well recognized that the wavelet coefficients in different subbands are statistically correlated, resulting in the fact that the product of the marginal distributions of wavelet coefficients is not accurate enough to(More)
Previously, we developed a novel microRNA (miRNA) delivery system based on bacteriophage MS2 virus-like particles (MS2 VLPs). In this current study, we used this system to transport miR-146a into human peripheral blood mononuclear cells (PBMCs), and demonstrated the inhibition of osteoclastogenesis in precursors. Two cytokines, receptor activator of NF-κB(More)