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Laboratories are increasingly requested to perform CYP2C19 genetic testing when managing clopidogrel therapy, especially in patients with acute coronary syndrome undergoing percutaneous coronary intervention. To ensure high quality molecular testing and ascertain that the referring clinician has the correct information for CYP2C19 genotype-directed(More)
BACKGROUND Coronary artery disease (CAD) is a major vascular complication of diabetes mellitus and reveals high mortality. Up to 30% of diabetic patients with myocardial ischemia remain asymptomatic and are associated with worse prognosis compared to non-diabetic counterpart, which warrants routine screening for CAD in diabetic population. The purpose of(More)
—For many vehicular safety applications, it is critical to timely and reliably deliver multimedia data from a traveling vehicle to a roadside access point (AP) in an error-prone vehicular ad hoc network (VANET), which is a typical uplink scenario for drive-thru Internet. To achieve this goal, we propose a cooperative retransmission scheme that exploits a(More)
BACKGROUND Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of pathogenic autoantibodies. Recent studies suggest that microRNAs (miRNAs) play an essential role in immunoregulation and may be involved in the pathogenesis of SLE. Therefore, it was of interest to investigate the potential therapeutic application(More)
BACKGROUND Global warming and shifted precipitation regimes increasingly affect species abundances and distributions worldwide. Despite a large literature on species' physiological, phenological, growth, and reproductive responses to such climate change, dispersal is rarely examined. Our study aims to test whether the dispersal ability of a non-native,(More)
In this paper, a novel approach to texture retrieval using independent component analysis (ICA) in wavelet domain is proposed. It is well recognized that the wavelet coefficients in different subbands are statistically correlated, resulting in the fact that the product of the marginal distributions of wavelet coefficients is not accurate enough to(More)
Aging has been associated with mitochondrial DNA damage. P66Shc is an age-related adaptor protein that has a substantial impact on mitochondrial metabolism through regulation of the cellular response to oxidative stress. Our study aimed to establish a D-galactose (D-gal)-induced inner ear aging mouse model and to investigate the potential role of p66Shc and(More)
BACKGROUND We investigated whether serum glycated albumin (GA) levels are related to coronary collateralization in type 2 diabetic patients with chronic total occlusion. METHODS Blood levels of GA and glycosylated hemoglobin (HbA1c) were determined in 317 diabetic and 117 non-diabetic patients with stable angina and angiographic total occlusion of at(More)