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- Laura J. Scott, Karen L. Mohlke, +38 authors Michael Boehnke
- Science
- 2007
Identifying the genetic variants that increase the risk of type 2 diabetes (T2D) in humans has been a formidable challenge. Adopting a genome-wide association strategy, we genotyped 1161 Finnish T2D… (More)
- Peter J. Calcraft, Abdelilah Arredouani, +18 authors Michael X Zhu
- Nature
- 2009
Ca(2+) mobilization from intracellular stores represents an important cell signalling process that is regulated, in mammalian cells, by inositol-1,4,5-trisphosphate (InsP(3)), cyclic ADP ribose and… (More)
- Hong-zhen Hu, Rui Xiao, +4 authors Michael X Zhu
- Journal of cellular physiology
- 2006
Transient receptor potential vanilloid (TRPV) channels are polymodal detectors of multiple environmental factors, including temperature, pH, and pressure. Inflammatory mediators enhance TRPV function… (More)
- Rui Xiao, J Q Tang, Chunbo Wang, Craig K Colton, Jinbin Tian, Michael X Zhu
- The Journal of biological chemistry
- 2008
Transient receptor potential channels are involved in sensing chemical and physical changes inside and outside of cells. TRPV3 is highly expressed in skin keratinocytes, where it forms a nonselective… (More)
- Rui Xiao, Qijun Zhao, David Zhang, Pengfei Shi
- Pattern Recognition
- 2011
Manifold learning has been successfully applied to facial expression recognition by modeling different expressions as a smooth manifold embedded in a high dimensional space. However, the assumption… (More)
The posttranscriptional mechanisms that control the cycling of circadian clock protein levels are not known. Here we demonstrate a role for protein phosphatase 2A (PP2A) in the cyclic expression of… (More)
- Chip Hong Chang, Pengfei Xu, Rui Xiao, Thambipillai Srikanthan
- IEEE Transactions on Neural Networks
- 2005
Color quantization (CQ) is an image processing task popularly used to convert true color images to palletized images for limited color display devices. To minimize the contouring artifacts introduced… (More)
- Jae Man Lee, Martin Wagner, +4 authors David D. Moore
- Nature
- 2014
Autophagy is an evolutionarily conserved catabolic process that recycles nutrients upon starvation and maintains cellular energy homeostasis. Its acute regulation by nutrient-sensing signalling… (More)
- Elizabeth N Genda, Joshua G Jackson, +10 authors Michael B Robinson
- The Journal of neuroscience : the official…
- 2011
Efficient excitatory transmission depends on a family of transporters that use the Na(+)-electrochemical gradient to maintain low synaptic concentrations of glutamate. These transporters consume… (More)
- Rui Xiao, Jinbin Tian, J Q Tang, Michael X Zhu
- Cell calcium
- 2008
TRPV3 is a non-selective cation channel activated by warm to hot temperatures. In rodents, TRPV3 is highly expressed in basal keratinocytes of skin and oral/nasal epithelia. TRPV3 knockout mice… (More)