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Aging is associated with progressive arterial stiffening and widening of the pulse pressure, resulting in a high prevalence of systolic hypertension. The contribution of increased aortic thickness to this process and to essential hypertension has been poorly characterized. With transesophageal echocardiography, aortic thickness and diameter can be measured.(More)
Posterior displacement of the mitral valve with billowing into the left atrium has been the major echocardiographic criterion used for the diagnosis of mitral valve prolapse (MVP). However, the current criteria are limited by the influence of hemodynamic factors on the degree of prolapse, whereas complications such as mitral regurgitation, endocarditis, and(More)
Early atherosclerotic changes in the carotid artery and thoracic aorta have been examined by high-frequency ultrasound measuring of intimal-medial thickness and stiffness. Whether changes in stiffness and thickness occur in parallel and whether the determinants of stiffness and thickness in the two vessels are similar is unknown. To examine the relation(More)
We have demonstrated that the pulmonary venous and transmitral atrial duration, and the difference between the 2 are independent of age and not influenced by hypertension, but have a high interobserver variability and range of variability. Enthusiasm for this parameter with the currently available recording techniques must be tempered by the high(More)
BACKGROUND AND AIMS OF THE STUDY Mitral valve prolapse due to floppy mitral valve (MVP/FMV) is a common valvular abnormality with a variable clinical course. Flail mitral valve leaflet resulting in severe mitral regurgitation is a complication of MVP/FMV. METHODS In order to understand the structural correlates of flail mitral valve leaflet in MVP, we(More)
BACKGROUND The synchronization of the uterus and mature eggs at the molecular level is the key factor in embryo transfer, and the regulation of synchronization depends on a variety of cytokines. C-reactive protein (CRP), as the first acute phase reaction protein, is involved in the entire process of embryo transfer. The study is designed to investigate the(More)
OBJECTIVE To compare the incidence of metabolic disorders (MS) in patients with primary aldosteronism (PA) and essential hypertension (EH). METHODS MS prevalence was observed in 200 EH patients (male 104) and 220 PA patients (male 117) hospitalized to our hospital from August 2005 to March 2007. RESULTS (1) The prevalence of MS in PA group was(More)
Objective: To investigate the role of ORAI1 in the balloon injury-induced rat carotid artery neointimal formation and the relationship between ORAI1 and sodium and calcium exchanger(NCX)1. Methods: According to condition of carotid artery balloon injury and observation time, Sprague Dawley rats were divided into 3 groups including sham group, 7 days injury(More)
OBJECTIVE To investigate the effects and related mechanism of 5-aza-2'-deoxycytidine(Aza) on endothelial function in Hyperhomocysteinemia rats. METHODS Adult male SD rats were divided into 3 groups (n=7 each): control group, hyperhomocysteinemia (HHcy) group and Aza group according to the random number table. Control group rats were fed with normal diet.(More)
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