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Solid-state disks (SSDs) are becoming widely used in personal computers and are expected to replace a great portion of magnetic disks in servers and supercomputers. Although many high-speed SSDs are present in the market, both the design of hardware architecture and the details of the flash translation layer (FTL) are not well known. Meanwhile, in the(More)
As one of the fundamental infrastructures for cloud computing, data center networks (DCN) have recently been studied extensively. We currently use pure software-based systems, FPGA based platforms, e.g., NetFPGA, or OpenFlow switches, to implement and evaluate various DCN designs including topology design, control plane and routing, and congestion control.(More)
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), one of the first found cancer-associated long noncoding RNAs (lncRNAs), involves in the development and progression of many types of tumors. An aberrant expression of MALAT1 was observed in hepatocellular carcinoma, cervical cancer, breast cancer, ovarian cancer, and colorectal cancer.(More)
The stability and membrane localization of the transforming growth factor-β (TGF-β) type I receptor (TβRI) determines the levels of TGF-β signalling. TβRI is targeted for ubiquitylation-mediated degradation by the SMAD7-SMURF2 complex. Here we performed a genome-wide gain-of-function screen and identified ubiquitin-specific protease (USP) 4 as a strong(More)
BACKGROUND Capsule endoscopy (CE) has been widely used in clinical practice. OBJECTIVE To provide systematically pooled results on the indications and detection, completion, and retention rates of small-bowel CE. DESIGN A systematic review. MAIN OUTCOME MEASUREMENTS We searched the PubMed database (2000-2008) for original articles relevant to(More)
Anterior approach was extensively used in surgical treatment of multilevel cervical spondylotic myelopathy. Following anterior decompression, many different reconstructive techniques (multilevel ACDF, hybrid construct and long corpectomy) all had satisfied outcomes. However, there are few studies focusing on the comparison of these three reconstructed(More)
This review provides an overview of the pharmacogenetics of membrane transporters including selected ABC transporters (ABCB1, ABCC1, ABCC2, and ABCG2) and OATPs (OATP1B1 and OATP1B3). Membrane transporters are heavily involved in drug clearance and alters drug disposition by actively transporting substrate drugs between organs and tissues. As such,(More)
The repair of reactive oxygen species-induced base lesions and single strand breaks (SSBs) in the nuclear genome via the base excision (BER) and SSB repair (SSBR) pathways, respectively, is well characterize, and important for maintaining genomic integrity. However, the role of mitochondrial (mt) BER and SSBR proteins in mt genome maintenance is not(More)
Lysozymes, especially c-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. The relatives of c-type lysozymes, alpha-lactalbumins, however, are only found in mammalian milk and possess a distinct biological function. These two proteins, having similar amino(More)
Conductometric semiconducting metal oxide gas sensors have been widely used and investigated in the detection of gases. Investigations have indicated that the gas sensing process is strongly related to surface reactions, so one of the important parameters of gas sensors, the sensitivity of the metal oxide based materials, will change with the factors(More)