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  • Ruediger Nave, Werner R. Meyer, Rainer Fuhst, Karl Zech
  • Chemistry, Medicine
  • Pulmonary pharmacology & therapeutics
  • 2005 (First Publication: 1 December 2005)
  • Ciclesonide, an inhaled corticosteroid (ICS) with prolonged anti-inflammatory activity, is being developed for the treatment of asthma. Fatty acid conjugation of ICS is thought to be related toContinue Reading
  • Ruediger Nave, Rolf Herzog, Aziz Laurent, Mark A Wingertzahn
  • Medicine
  • Clinical therapeutics
  • 2009 (First Publication: 1 December 2009)
  • BACKGROUND Ciclesonide, an intranasal corticosteroid, is administered as a prodrug and is converted to the active metabolite, desisobutyryl ciclesonide, in the upper and lower airways. PreviousContinue Reading
  • Ruediger Nave, Kulasiri A. Gunawardena, Karl Zech, Thomas D. Bethke
  • Medicine
  • International journal of clinical pharmacology…
  • 2006
  • OBJECTIVE To evaluate whether the inflammatory process and bronchial constriction associated with asthma influence the pulmonary distribution and airway penetration of inhaled ciclesonide byContinue Reading