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Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma
- M. Austinat, R. Dunsch, C. Wittekind, A. Tannapfel, R. Gebhardt, F. Gaunitz
- Medicine, Biology
- Molecular Cancer
- 18 February 2008
Aberrant Wnt-signaling caused by mutants of β-catenin, a key regulator of the canonical Wnt-signaling pathway, is frequently detected in cancer. Only recently, it was suggested that in hepatocellular… Expand