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  • Tana Koudelakova, Radka Chaloupkova, +11 authors Jiří Damborský
  • Chemistry, Medicine
  • Angewandte Chemie
  • 2013 (First Publication: 11 February 2013)
  • Mutations targeting as few as four residues lining the access tunnel extended enzyme’s half-life in 40% dimethyl sulfoxide from minutes to weeks (4,000-fold) and increased its melting temperature byContinue Reading
  • Klára Sušánková, Rudiger Ettrich, Ladislav Vyklický, Jan Teisinger, Viktorie Vlachova
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 2007 (First Publication: 11 July 2007)
  • The transient receptor potential vanilloid receptor-1 (TRPV1) is a sensory neuron-specific nonselective cation channel that is gated in response to various noxious stimuli: pungent vanilloids, lowContinue Reading
  • Jan Benedikt, Abdul Samad, Rudiger Ettrich, Jan Teisinger, Viktorie Vlachova
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 2009 (First Publication: 1 July 2009)
  • The ankyrin transient receptor potential channel TRPA1 is a sensory neuron-specific channel that is gated by various proalgesic agents such as allyl isothiocyanate (AITC), deep cooling or highlyContinue Reading
  • Alexander Dulebo, Rudiger Ettrich, Rudolf Lucas, David Joseph Kaftan
  • Chemistry, Medicine
  • Current pharmaceutical design
  • 2012 (First Publication: 1 September 2012)
  • The lectin-like domain of Tumor Necrosis Factor (TNF), mimicked by the TIP peptide, activates amiloride-sensitive sodium uptake in type II alveolar epithelial cells and as such increases alveolarContinue Reading
  • Kristýna Slámová, Natallia Kulik, Martin Fiala, Jana Krejzová-Hofmeisterová, Rudiger Ettrich, Vladimír Křen
  • Biology, Medicine
  • Protein expression and purification
  • 2014 (First Publication: 1 March 2014)
  • β-N-acetylglucosaminidases from the family 84 of glycoside hydrolases form a small group of glycosidases in eukaryotes responsible for the modification of nuclear and cytosolic proteins withContinue Reading