Ruchi Parikh

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Corticotropin-releasing factor (CRF) is a neuropeptide commonly associated with the hypothalamic-pituitary adrenal axis stress response. Upon release, CRF activates two G protein-coupled receptors (GPCRs): CRF receptor 1 (CRFR1) and CRF receptor 2 (CRFR2). Although both receptors contribute to mood regulation, CRFR1 antagonists have demonstrated anxiolytic(More)
Social media sites such as Twitter and Facebook have emerged as popular tools for people to express their opinions on various topics. The large amount of data provided by these media is extremely valuable for mining trending topics and events. In this paper, we build an efficient, scalable system to detect events from tweets (ET). Our approach detects(More)
Adhesive bonding to dentin can fail if the dentin is too wet during application of the bonding resin. This study compared the in vitro 24-hour microtensile bond strength of teeth restored at four different priming times at the gingival cavity wall of Class II resin composite restorations. After IRB approval, six pairs of extracted third molars (yielding 12(More)
Permanent Neonatal Diabetes Mellitus (PNDM), is a rare monogenic disorder, caused by activating mutations of the KATP channel. The most severe clinical form of PNDM presents as Developmental delay, Epilepsy and Neonatal Diabetes (DEND) syndrome. Diagnosis is confirmed by genetic mutation testing. Oral sulfonylurea therapy improves neurological outcome.
Due to non-affordability of GnRH analogues (GnRHa), Medroxy Progesterone Acetate (MPA) is still used as a treatment option in girls with CPP in India. The aim here is to study the clinical features of girls with CPP in respect to the age at presentation, etiology and outcome as per the medication used for their treatment (GnRHa vs MPA). Retrospective study(More)
BACKGROUND Fanconi Bickel Syndrome is a rare, autosomal recessive, disorder of carbohydrate metabolism. Presence of hypercalciuria is rare. CASE CHARACTERISTICS 4.5-years-old boy presented with growth failure, hepatomegaly, rickets, fasting hypoglycemia with postprandial hyperglycemia, fanconi syndrome and hypercalciuria. OUTCOME A rare mutation in(More)
Obesity and decreased final height are described in children with CAH 21OHD. Of 119 children (50 M, 69F;79 Salt Wasters(SW), 40 Simple Virilizers (SV)) diagnosed over 24 years, various growth parameters were studied in 43 children with regular follow up for 5 years or more. Clinical data, anthropometry, genotype, hormonal and biochemical profile were(More)
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