Ruan Goller

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IL-2 is given to patients with advanced melanoma or renal carcinoma. However this therapy is accompanied by severe side effects including the VLS that closely resembles septic shock.In order to investigate the pathogenesis of the symptoms observed we took 8 longitudinal plasma samples from 20 patients during the first 24 hours after administration of IL-2.(More)
ICTO is a rare congenital disorder characterized by bone resorption affecting mainly the carpal and tarsal bones [1]. Previously it was known as idiopathic multicentric osteolysis and was first described in 1838 by this term [2]. Tyler et al. also preferred the term idiopathic multicentric osteolysis (1976) as this encompassed the wide array of descriptive(More)
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