Ru-lai Yang

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BACKGROUND Tandem mass spectrometry (MS/MS) has been available in China for 8 years. This technique makes it possible to screen for a wide range of previously unscreened inborn errors of metabolism (IEM) using a single test. This 3-year pilot study investigated the screening, diagnosis, treatment and outcomes of IEM in symptomatic infants and children. (More)
OBJECTIVE To investigate effects of developmental lead exposure on nitric oxide synthase (NOS) activity in different brain regions and on N-methyl-D-aspartate (NMDA) receptor mRNA expression in the hippocampus of rats. On the basis of these observations, we explored possible mechanisms by which lead exposure leads to impaired learning and memorizing(More)
BACKGROUND It is reported that the infant mortality (IM) rate decreased rapidly in China and the life expectancy (LE) also had a high increase. Our objective was to determine the health status of the Chinese population by investigating IM and LE and their inter-relationship. MATERIAL AND METHODS Based on a literature review on the history and current(More)
Variations of amino acid, free carnitine and acylarnitine profiles analysed by tandem mass spectrometry in newborns during their first four weeks of life Aims Electrospray ionization-tandem mass spectrometry (MS/ MS) has increasingly been advocated for expanded newborn screening and for the early diagnosis of amino acidemias, fatty acid oxidation disorders,(More)
OBJECTIVES This is a population based descriptive study that examined the trends in childhood mortality among under five children and the major causes under five mortality in Zhejiang Province, China. METHODS A population-based survey was conducted through a province-level surveillance network. The mortality rate and leading causes of death for children(More)
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