Ru¨diger Hehlmann

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  • R Hehlmann
  • Current topics in microbiology and immunology
  • 1976
There is a strong association between viruses and the development of human malignancies. A group of oncogenic DNA viruses exists in the human population today, members of which serve as infectious agents of cancer worldwide. The group includes the Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, human papillomaviruses and human polyomaviruses.(More)
The human genome contains at least 50 copies of the human endogenous retrovirus K (HERV-K) family which is related to the mouse mammary tumor virus (MMTV). Some members have been shown to be transcriptionally active and to have large open reading frames. Using the RT-PCR method we have investigated the HERV-K env transcription pattern in several malignant(More)
The mouse melanoma B16 contains particles encapsulating high molecular weight RNA of 60–70S size associated with a reverse transcriptase. The [3H]DNA synthesized by these particles possesses homology with RNA isolated from a hamster melanoma and from three human malignant melanomas. Im Mäusemelanom B16 läßt sich eine partikelgebundene hochmolekulare, bei(More)
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