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Anti-HIV-1 activities of 20 tetrapyrroles (hematoporphyrin derivatives, meso-tetraphenylporphyrins, a chlorin, and a phthalocyanine) were predicted based on their molecular structures using artificial neural networks. The molecular structures were optimized by HyperChem program using MM+ molecular mechanics and conformational search for the global minimum(More)
The effect of regular intake of low doses of an effervescent multivitamin preparation on the free-radical-producing activity of murine peritoneal macrophages under conditions resembling a possible infection was studied in vitro. Initially, several groups of mice were fed a basal diet and given, for 2 weeks, water without or with supplementation of either(More)
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