Royce M Hazard-Leonards

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Expression of many cell type-specific genes is correlated with a reduced level of cytosine methylation and some results argue that genetic programmes may be activated by a reduction in DNA methylation. During embryogenesis, however, when many genes are activated in specific cell lineages, it has not been demonstrated that they are hypomethylated prior to(More)
Early studies on lens induction suggested that the optic vesicle, the precursor of the retina, was the primary inducer of the lens; however, more recent experiments with amphibians establish an important role for earlier inductive interactions between anterior neural plate and adjacent presumptive lens ectoderm in lens formation. We report here experiments(More)
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