PURPOSE To critically appraise, compare and summarize the measurement properties of self-report fatigue questionnaires validated in patients with multiple sclerosis (MS), Parkinson's disease (PD) or stroke. METHODS MEDLINE, EMBASE, PsycINFO, CINAHL and SPORTdiscus were searched. The COnsensus-based Standards for the selection of health Measurement… (More)
To investigate the longitudinal association between fatigue and physical activity in Parkinson's disease (PD) and determine whether this association is distorted by potential confounders. Data from baseline, 3, 6, and 12 week assessments in a single blind randomized clinical trial with cross-over design were used (N = 153). The Multidimensional Fatigue… (More)
INTRODUCTION The Multidimensional Fatigue Inventory (MFI) is commonly used in patients with Parkinson's disease (PD). However, most measurement properties have not been investigated in this population. The aim of this study was to investigate internal consistency, test-retest reliability, measurement error, structural validity, and floor and ceiling effects… (More)
Kwakkel This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Abstract Background Factors contributing to subjective fatigue in patients with idiopathic Parkinson's disease (PD) are not well known. This makes it difficult to manage fatigue effectively in PD.
The specific binding of the dopamine antagonist 3H-spiperone to lymphocytes from a healthy control group (n = 40), a group of acute, unmedicated schizophrenic patients (n = 27), and a psychiatric control group (n = 16) was investigated. There were no differences in binding parameters between the healthy controls (Bmax 2.6 +/- 0.7 fmoles/10(6) cells; Kd 0.17… (More)
OBJECTIVE To investigate the predictive value of gait speed for community walking in Parkinson's disease and to develop a multivariate prediction model for community walking. DESIGN Data from baseline assessments in a randomized clinical trial were used. SUBJECTS A total of 153 patients with Parkinson's disease were included. METHODS Community walking… (More)
OBJECTIVE To investigate the longitudinal association between the impact of fatigue and health-related quality of life and to determine if potential confounders distorted this association. DESIGN Baseline, 3-, 6- and 12-week assessments of a randomized clinical trial were used. SETTING Outpatient rehabilitation centre. SUBJECTS Patients with… (More)
The simultaneous determination of serum catecholamine (CA) and their receptors in blood cells offers the possibility of evaluating disturbances of the dopamine (DA) and noradrenaline (NA) neuronal systems in man. High-affinity binding sites for 3H-yohimbine in platelets, 3H-DHA in granulocytes, and 3H-spiperone in lymphocytes from healthy control persons,… (More)