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Oxygen consumption and the activities of the selenoenzyme glutathione peroxidase, and of the hexose monophosphate shunt were lower than normal in neutrophils from Se deficient cattle. However, these activities and the activity of Cu/zinc superoxide dismutase were unaffected in neutrophils from Cu deficient cattle. These results are discussed with reference(More)
The effects of selenium deficiency on the responses to Candida albicans infection were examined in mice. When selenium-deficient and selenium-supplemented mice were given i.v. injections of 0.1 ml suspensions of 1 X 10(5) or 5 X 10(4) C. albicans in 0.9% sterile saline, deaths in the selenium-deficient animals started after 2.5-3.5 d compared with 7-8.5 d(More)
Selenium deficiency in rats impairs the ability of neutrophils and peritoneal macrophages to kill Candida albicans organisms in vitro. In contrast, killing of Salmonella typhimurium and Staphylococcus aureus organisms is unaffected by the deficiency. Survival of rats after intraperitoneal injection of 8 X 10(7) S. aureus organisms was not affected by Se(More)
Both selenium and copper deficiencies in rats caused morphological changes in erythrocytes but only copper deficiency resulted in anaemia. Similar but less severe morphological changes occurred when rats consuming selenium- and copper-adequate diets had their food intake restricted to that of the copper-deficient animals. Since selenium deficiency did not(More)
Pain survey was administered to 77 patients undergoing nerve conduction (NC) and needle electromyographic (EMG) procedures. The patient was asked to rate the pain immediately after the electrodiagnostic study was completed. Statistical analyses were performed to determine if there were relationships between pain and any of the technologic and physiologic(More)
Neutrophils from cattle with copper deficiency induced by molybdenum (0.052 mmol molybdenum kg-1 diet) or iron (8.95 mmol iron kg-1 diet) had an impaired ability to kill ingested Candida albicans and were less viable than those from copper-supplemented cattle in in vitro tests of function. Restricted intake (80 per cent of ad libitum) of a copper-adequate(More)
Transit of 3T3 cells from quiescence to S phase requires an adequate supply of Zn2+ during the second half of the transition. The nature of this requirement has been investigated. Completion of the Zn2(+)-dependent process required ongoing mRNA and protein synthesis but could be accomplished in serum-free medium. Combination of low Zn2+ availability with(More)