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Specific DNA recognition mediated by a type IV pilin
- A. Cehovin, P. Simpson, +8 authors V. Pelicic
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 5 February 2013
Natural transformation is a dominant force in bacterial evolution by promoting horizontal gene transfer. This process may have devastating consequences, such as the spread of antibiotic resistance or… Expand
Tetrahydropyridinium bromide: Useful synthon to functionalized pyrrolidines
1-benzyl-5-(ethoxycarbonyl)-2,3,4,5-tetrahydropyridinium bromide undergoes ring contraction with a series of nucleophiles, getting 2,2-disubstitued pyrrolidines. Moreover, from some of the new… Expand
Tetrahydropyridinium Bromide: Useful Synthon to Functionalized Pyrrolidines.
Piperidinium salt (I) undergoes ring contraction with a range of nucleophiles to furnish 2,2-disubstituted pyrrolidines.