Ross A. Pigeau

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The stimulant modafinil has proved to be an effective treatment modality for narcolepsy and related sleep disorders and is also being studied for use during sustained military operations to ameliorate the effects of fatigue due to sleep loss. However, a previous study reported that a relatively large, single dose of modafinil (300 mg), administered to(More)
Self-monitoring refers to the ability to assess accurately one's own performance in a specific environment. The present study investigated the effects of the stimulating drugs modafinil (300 mg) and d-amphetamine (20 mg) on the ability to self-monitor cognitive performance during 64 h of sleep deprivation (SD) and sustained mental work. Two cognitive tasks(More)
The future of command and control is not Command and Control. In fact, the term Command and Control has become a significant impediment to progress. This paper presents and discusses key terms that form the core of a new conceptual foundation; one that can provide a point of departure for the systematic exploration of future “command and control.” Three(More)
INTRODUCTION Modern military operations may require pharmaceutical methods to sustain alertness and facilitate sleep in order to maintain operational readiness. In operations with very limited sleep windows, hypnotics with very short half-lives (e.g., zaleplon, t(1/2) 1 h) are of interest, while with longer sleep opportunities, longer acting agents (e.g.,(More)
INTRODUCTION This study was an extension into an operational setting of previous laboratory work investigating the use of zopiclone and melatonin to facilitate early circadian sleep in transport aircrew. The previous laboratory-based study demonstrated that both melatonin and zopiclone were effective in inducing early circadian sleep without impacting on(More)
Reactivity to photic stimulation was studied in 16 subjects who were divided into 2 groups based on the relative amounts of spontaneous EEG alpha produced during a 4 min eyes-closed baseline condition. During the experimental session the subjects were presented with thirteen 1 min periods of sinusoidally modulated light stimulation at frequencies ranging(More)
INTRODUCTION Current military operations often require pharmaceutical methods to sustain alertness and facilitate sleep in order to maintain operational readiness. This study was designed to compare the sleep-inducing power of four medications. METHOD There were 9 men and 14 women, ages 21-53 yr, who were assessed for psychomotor performance before and(More)
OBJECTIVE Several factors, such as homeostatic and circadian influences, may affect the density of cortical and subcortical arousals (AR). The purpose of this study was to examine the time-of-night and the first night effect on AR response. METHODS AR were classified into microarousals (MA), phases of transitory activation (PAT), delta (D-burst) and(More)
Rationale. Modafinil is a wake-promoting agent that affects hypothalamic structures involved in the homeostatic and circadian regulation of vigilance. Administered during sleep deprivation, it reduces the need for prolonged recovery sleep and decreases the rebound in EEG slow-wave activity. These diachronic effects suggest an action of modafinil on a(More)
OBJECTIVE Arousal (AR) from sleep is associated with an autonomic reflex activation raising blood pressure and heart rate (HR). Recent studies indicate that sleep deprivation may affect the autonomic system, contributing to high vascular risk. Since in sleep disorders a sleep fragmentation and a partial sleep deprivation occurs, it could be suggested that(More)