Rosemary Howell

Learn More
All-trans-retinoic acid (ATRA) has been proved to be an effective treatment for acute promyelocytic leukemia (APL), inducing remission in more than 90% of cases. Treatment of APL in pregnancy is controversial as the use of ATRA has been questioned due to the teratogenic effect of retinoids. We report a case of pregnancy in a woman exposed to ATRA during the(More)
Although AIDS was described as a new and distinct diseaseI in 1981, there have been few reports of the oral manifestations of the disease in children. 2-4 Early reports described soft tissue lesions but provided little information in regard to dental caries. In recent years, as greater numbers of children with AIDS have been examined, the problem of(More)
PURPOSE The performance of NHS U.K. hospitals is under continuous scrutiny as they are constantly under pressure to perform well. A recent document published by an independent body has recommended a host of clinical indicators to assess non-financial performance of hospitals. This study aims to critically analyse the performance of a single U.K. hospital(More)
This study investigated the prevalence of oral soft tissue lesions in children infected with HIV and the relationship of CD4 lymphocyte levels with the prevalence of those lesions. Sixty HIV-positive children enrolled in the Children's Hospital AIDS Program (age 5.8 +/- 3 years) were selected for study. Only five subjects (8%) had healthy gingiva and a low(More)
OBJECTIVE To appraise critically the published randomized controlled trials (RCTs) comparing carbon dioxide (CO2) with normal saline (NS) as distension medium for diagnostic hysteroscopy. DESIGN Systematic review and meta-analysis of RCTs. SETTING Outpatient and inpatient hysteroscopy clinics. PATIENT(S) Women undergoing diagnostic hysteroscopy. (More)
  • 1