Rose Boyle

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A crucial aim upon the completion of the human genome is the verification and functional annotation of all predicted genes and their protein products. Here we describe the mapping of peptides derived from accurate interpretations of protein tandem mass spectrometry (MS) data to eukaryotic genomes and the generation of an expandable resource for integration(More)
Phospholipase A(2) type IVA (IVAPLA(2)) is a cytosolic enzyme that on activation selectively releases arachidonic acid (AA) from cell membrane phospholipids. Both AA and lysophospholipid, products of the enzymic reaction, can function as signal transducers in cellular interactions. The enzyme is present in most cells, including polymorphs, eosinophils, and(More)
The erythrocyte and plasma fatty acid compositions of children with autism were compared in a case-control study with typically developing (TD) children and with children showing developmental delay (DD). Forty-five autism subjects were age-matched with TD controls and thirty-eight with DD controls. Fatty acid data were compared using paired t tests. In(More)
In this formulation, Doxorubicin (Dox) was conjugated to Poly (lactic-co-glycolic acid) (PLGA), and formulated via the solvent-diffusion techniques into nanoparticles. The surface of the nanoparticles was subsequently linked with Poly (ethylene glycol) (PEG) and Arg-Gly-Asp (RGD) peptide to achieve both passive and active targeting moieties. The(More)
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