Rosanna Marty

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The onset of synaptogenesis was studied in the temporal cortex of rat fetuses whose age ranged between 15 and 19 days of gestation. First synapses were found at a surprisingly early stage of cortical development: on day 16. These contacts showed relatively few vesicles and very inconspicuous membrane-thickenings. They were located in the marginal layer,(More)
The study of the postnatal maturation of the ventral cochlear nuclei (VCN) and the dorsal cochlear nuclei (DCN) was carried out on the cat by means of recordings of the extra-cellular neuronal activity. At birth it is already possible to obtain toneburst responses in the VCN and DCN. At this age the responses are characterised by a small number of spikes(More)
Rat fetuses received tritiated thymidine on one of each of the following days of gestation: 9, 10, 11, 12, 13, 14 and 16. Animals were sacrificed on day 1 post partum. Perpendicular and tangential sections including temporal cortex were studied by electron microscopy and light microscopic autoradiography. Our results suggest that the formation of(More)
Early cortical neurogenesis and synaptogenesis are discussed with reference to observations made in fetal and postnatal rat temporal cortex. Thymidine autoradiography was used to determine the time of origin of cortical neurons, particularly of layer I. Earliest neurons--CRs--form between FD 12 and 15, whereas the period of maximal formation of layer I(More)
The maturation of the stato-acoustic nerve in the cat was studied by light and electron microscopy from the fetal stage to the adult. Measurement of the outer diameter of the fibers and the study of the myelination process revealed that myelination begins earlier for the vestibular nerve than for the cochlear nerve: by the fifty-third day of gestation 64%(More)
Myelinated cell bodies of spiral ganglion in kittens during development can first be distinguished by light microscopic observation at the end of the first postnatal week. By mean of electron microscopic observation, the first signs of myelinated perikarya can be observed around the time of birth. Myelination is preceded by the ensheathment of the ganglion(More)
Newborn rats received an intracisternal injection of 6-hydroxydopamine (100 micrograms) within 16 h after birth. Treatment effects upon noradrenaline uptake (with or without desmethylimipramine pre-incubation), endogenous noradrenaline, dopamine, and serotonin were biochemically assayed. Noradrenaline uptake and endogenous noradrenaline content were(More)
In human alcoholic cirrhotic encephalopathy, most of astrocytes of the cerebral cortex appear as Alzheimer type II cells. Thus, they cannot be visualized by the immunocytochemical detection of Glial Fibrillary Acidic protein (GFAP). However, fibrous astrocytes present in layer I of the cortex and in the vicinity of the white matter are GFAP positive. This(More)
Two distinct categories of facts are deduced from a neuropathological study of the Ammon's horn, in particular the Sommer Sector, afflicted with alcoholic cirrhotic encephalopathy. In the pyramidal neurons of the CA1 layer, there are unquestionably paired filaments in a helical form, which correspond to the now classic "paired helical filaments". On the(More)