Myelodysplastic syndromes (MDS) are hematopoietic stem cell disorders characterized by dysplastic, ineffective, clonal and neoplastic hematopoiesis. MDS represent a complex hematological problem: differences in disease presentation, progression and outcome have necessitated the use of classification systems to improve diagnosis, prognostication, and… (More)
A case of parvovirus B19-induced pure red cell aplasia occurring in a heart transplant recipient is reported. The diagnosis of this rare but clinically important complication can be suspected on the basis of the pathognomonic morphological features of the bone marrow.
KEY CLINICAL MESSAGE A case of feverish benign neutropenia occurring in a diabetic patient receiving pregabalin for peripheral neuropathy is reported. Although pregabalin-induced neutropenia is very rare, it is important to keep in mind that this drug like other anticonvulsants used for neuropathic pain, can cause severe neutropenia.
The epidemiology of fungal infections in patients with hematologic malignancies: the SEIFEM-2004 study T he percentage of patients who develop invasive fungal infections (IFI) has increased dramatically in recent decades. Most of these infections occur in patients with hematologic malignancies. This increase is attributed to host defense impairment due to… (More)