Rosalia Ferro

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Inhibitors of the cyclo-oxygenase component of prostaglandin-H2 synthetase, namely indomethacin and ibuprofen, are commonly used in the treatment of hemodynamically significant patent ductus arteriosus. These drugs are associated with serious adverse events, including gastrointestinal perforation, renal failure and bleeding. The role of paracetamol, an(More)
A therapeutic trial of transfusions with polymorphonuclear leukocyte concentrates was performed in newborn infants with bacterial sepsis proven by blood culture. With each transfusion, 20 ml/kg of a preparation obtained by continuous flow filtration leukapheresis, and containing 0.5 to 1 x 10(9) WBC, with less than 6% lymphocytes, was administered. Twenty(More)
We describe a 10-week-old hemophilic infant who developed a large-sized pseudoaneurysm of the radial artery after arterial puncture. Based on our previous experience, compression bandage was elected as first-line treatment. The clinical course was complicated by skin ulceration. However, compression bandage was continued, and complete thrombosis of the(More)
In premature infants with sepsis several defects of PMN function have been documented, suggesting that these infants can be equated to neutropenic patients. We, therefore, evaluated the effectiveness of PMN transfusion in 11 very premature newborn infants with sepsis (b.w.820-1200 g; g.a. 25-29 wks). The diagnosis of sepsis was established according to(More)
An apparatus was deviced allowing to shift from CPAP breathing by nasal prongs to nasal IPPV upon activation of the alarm of bradycardia (HR < 100/min) from the monitor attached to the patient. In 5 infants with apnoea of prematurity (bw 850-1200 g; g.a. 27-29 wks), HR, thoracic impedance and pressure in the respiratory circuit were continuously recorded,(More)
In the decade 1970-79, NEC was observed only in the period '76-'79, and only in infants weighing ≤ 1250 g, with sepsis and surviving at least 48 hours. In 1978 a trial of PMNs transf. to septic infants was started. In septic infants with the above characteristics admitted in '76-'79, we considered the following items: sex, weight, GA, SBP, a-b status, temp.(More)
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